| Saturday, 3 September 2022 |
| Birkenhead Park 3rd XV | Away Walkover | Ellesmere Port 2nd XV |
| New Brighton 2nd XV | Home Walkover | Winnington Park 3rd XV |
| Northwich 3rd XV | Home Walkover | Oswestry 2nd XV |
| Ruskin Park | 36 | 22 | Anselmians Mavericks (3rd XV) |
| Widnes 3rd XV | 24 | 19 | Helsby |
| Saturday, 10 September 2022 |
| Ellesmere Port 2nd XV | 17 | 39 | Ruskin Park |
| Hoylake 2nd XV | 57 | 15 | Birkenhead Park 3rd XV |
| New Brighton 2nd XV | 7 | 71 | Northwich 3rd XV |
| Winnington Park 3rd XV | 26 | 25 | Helsby |
| Saturday, 17 September 2022 |
| Birkenhead Park 3rd XV | 26 | 26 | Oswestry 2nd XV |
| Helsby | 69 | 0 | Anselmians Mavericks (3rd XV) |
| Northwich 3rd XV | 24 | 3 | Winnington Park 3rd XV |
| Ruskin Park | Home Walkover | Hoylake 2nd XV |
| Widnes 3rd XV | Home Walkover | Ellesmere Port 2nd XV |
| Saturday, 24 September 2022 |
| Ellesmere Port 2nd XV | 12 | 96 | Helsby |
| Hoylake 2nd XV | 7 | 26 | Widnes 3rd XV |
| New Brighton 2nd XV | 26 | 12 | Birkenhead Park 3rd XV |
| Winnington Park 3rd XV | Home Walkover | Anselmians Mavericks (3rd XV) |
| Saturday, 1 October 2022 |
| Anselmians Mavericks (3rd XV) | 12 | 14 | Ellesmere Port 2nd XV |
| Birkenhead Park 3rd XV | 5 | 65 | Northwich 3rd XV |
| Helsby | 38 | 49 | Hoylake 2nd XV |
| Ruskin Park | 86 | 3 | New Brighton 2nd XV |
| Widnes 3rd XV | 28 | 12 | Oswestry 2nd XV |
| Saturday, 8 October 2022 |
| Anselmians Mavericks (3rd XV) | 36 | 0 | Widnes 3rd XV |
| Hoylake 2nd XV | 66 | 0 | Oswestry 2nd XV |
| Saturday, 15 October 2022 |
| Hoylake 2nd XV | 10 | 50 | Anselmians Mavericks (3rd XV) |
| New Brighton 2nd XV | 12 | 15 | Widnes 3rd XV |
| Northwich 3rd XV | 24 | 30 | Ruskin Park |
| Oswestry 2nd XV | 7 | 69 | Helsby |
| Winnington Park 3rd XV | 40 | 24 | Ellesmere Port 2nd XV |
| Saturday, 22 October 2022 |
| Anselmians Mavericks (3rd XV) | Home Walkover | Oswestry 2nd XV |
| Birkenhead Park 3rd XV | 28 | 45 | Winnington Park 3rd XV |
| Ellesmere Port 2nd XV | 24 | 10 | Hoylake 2nd XV |
| Helsby | 54 | 12 | New Brighton 2nd XV |
| Widnes 3rd XV | Home Walkover | Northwich 3rd XV |
| Saturday, 29 October 2022 |
| Birkenhead Park 3rd XV | 8 | 75 | Ruskin Park |
| New Brighton 2nd XV | 7 | 24 | Anselmians Mavericks (3rd XV) |
| Northwich 3rd XV | 7 | 38 | Helsby |
| Oswestry 2nd XV | 45 | 17 | Ellesmere Port 2nd XV |
| Saturday, 5 November 2022 |
| Ellesmere Port 2nd XV | 29 | 15 | New Brighton 2nd XV |
| Northwich 3rd XV | Home Walkover | Anselmians Mavericks (3rd XV) |
| Ruskin Park | 26 | 8 | Winnington Park 3rd XV |
| Widnes 3rd XV | 32 | 15 | Birkenhead Park 3rd XV |
| Saturday, 12 November 2022 |
| Birkenhead Park 3rd XV | 7 | 24 | Helsby |
| New Brighton 2nd XV | 34 | 14 | Hoylake 2nd XV |
| Ruskin Park | 41 | 10 | Widnes 3rd XV |
| Winnington Park 3rd XV | 92 | 15 | Oswestry 2nd XV |
| Saturday, 19 November 2022 |
| Hoylake 2nd XV | 19 | 50 | Helsby |
| Saturday, 26 November 2022 |
| Anselmians Mavericks (3rd XV) | 54 | 19 | Birkenhead Park 3rd XV |
| Helsby | 31 | 10 | Ruskin Park |
| Hoylake 2nd XV | 0 | 36 | Northwich 3rd XV |
| Oswestry 2nd XV | 22 | 12 | New Brighton 2nd XV |
| Widnes 3rd XV | Home Walkover | Winnington Park 3rd XV |
| Saturday, 3 December 2022 |
| Birkenhead Park 3rd XV | 13 | 26 | Hoylake 2nd XV |
| Helsby | 19 | 3 | Winnington Park 3rd XV |
| Northwich 3rd XV | Home Walkover | New Brighton 2nd XV |
| Ruskin Park | Home Walkover | Ellesmere Port 2nd XV |
| Saturday, 7 January 2023 |
| Ellesmere Port 2nd XV | 12 | 10 | Anselmians Mavericks (3rd XV) |
| New Brighton 2nd XV | 17 | 37 | Ruskin Park |
| Oswestry 2nd XV | 17 | 17 | Widnes 3rd XV |
| Saturday, 14 January 2023 |
| Anselmians Mavericks (3rd XV) | 50 | 15 | Hoylake 2nd XV |
| Ellesmere Port 2nd XV | 15 | 7 | Winnington Park 3rd XV |
| Helsby | 89 | 0 | Oswestry 2nd XV |
| Ruskin Park | 17 | 14 | Northwich 3rd XV |
| Widnes 3rd XV | 7 | 5 | New Brighton 2nd XV |
| Saturday, 21 January 2023 |
| Anselmians Mavericks (3rd XV) | 5 | 0 | Oswestry 2nd XV |
| Hoylake 2nd XV | 27 | 27 | Ellesmere Port 2nd XV |
| New Brighton 2nd XV | 19 | 17 | Helsby |
| Widnes 3rd XV | 5 | 0 | Northwich 3rd XV |
| Winnington Park 3rd XV | 5 | 0 | Birkenhead Park 3rd XV |
| Saturday, 28 January 2023 |
| Anselmians Mavericks (3rd XV) | 17 | 17 | New Brighton 2nd XV |
| Ellesmere Port 2nd XV | 36 | 0 | Oswestry 2nd XV |
| Helsby | 24 | 22 | Northwich 3rd XV |
| Ruskin Park | Home Walkover | Birkenhead Park 3rd XV |
| Winnington Park 3rd XV | 29 | 34 | Hoylake 2nd XV |
| Winnington Park 3rd XV | 29 | 34 | Hoylake 2nd XV |
| Saturday, 4 February 2023 |
| Helsby | 40 | 5 | Ellesmere Port 2nd XV |
| Hoylake 2nd XV | 85 | 12 | New Brighton 2nd XV |
| Northwich 3rd XV | 117 | 5 | Birkenhead Park 3rd XV |
| Ruskin Park | 95 | 10 | Oswestry 2nd XV |
| Widnes 3rd XV | Home Walkover | Anselmians Mavericks (3rd XV) |
| Saturday, 11 February 2023 |
| Birkenhead Park 3rd XV | 31 | 31 | Widnes 3rd XV |
| New Brighton 2nd XV | 57 | 10 | Ellesmere Port 2nd XV |
| Northwich 3rd XV | 17 | 18 | Anselmians Mavericks (3rd XV) |
| Oswestry 2nd XV | 22 | 36 | Hoylake 2nd XV |
| Winnington Park 3rd XV | 20 | 29 | Ruskin Park |
| Saturday, 18 February 2023 |
| Helsby | 19 | 14 | Birkenhead Park 3rd XV |
| Northwich 3rd XV | 45 | 0 | Ellesmere Port 2nd XV |
| Northwich 3rd XV | 45 | 0 | Ellesmere Port 2nd XV |
| Oswestry 2nd XV | 34 | 40 | Winnington Park 3rd XV |
| Widnes 3rd XV | 5 | 38 | Ruskin Park |
| Saturday, 25 February 2023 |
| Birkenhead Park 3rd XV | 5 | 50 | New Brighton 2nd XV |
| Oswestry 2nd XV | 5 | 55 | Ruskin Park |
| Widnes 3rd XV | 72 | 7 | Hoylake 2nd XV |
| Winnington Park 3rd XV | 19 | 17 | Anselmians Mavericks (3rd XV) |
| Saturday, 4 March 2023 |
| Birkenhead Park 3rd XV | 0 | 39 | Anselmians Mavericks (3rd XV) |
| New Brighton 2nd XV | 17 | 25 | Oswestry 2nd XV |
| Northwich 3rd XV | 102 | 0 | Hoylake 2nd XV |
| Ruskin Park | 38 | 5 | Helsby |
| Widnes 3rd XV | Home Walkover | Winnington Park 3rd XV |
| Saturday, 11 March 2023 |
| Anselmians Mavericks (3rd XV) | 45 | 12 | Ruskin Park |
| Ellesmere Port 2nd XV | 5 | 47 | Birkenhead Park 3rd XV |
| Helsby | 40 | 0 | Widnes 3rd XV |
| New Brighton 2nd XV | 32 | 5 | Winnington Park 3rd XV |
| Northwich 3rd XV | Home Walkover | Oswestry 2nd XV |
| Saturday, 18 March 2023 |
| Anselmians Mavericks (3rd XV) | 35 | 7 | Helsby |
| Oswestry 2nd XV | Home Walkover | Birkenhead Park 3rd XV |
| Ruskin Park | Home Walkover | Hoylake 2nd XV |
| Widnes 3rd XV | Away Walkover | Ellesmere Port 2nd XV |
| Winnington Park 3rd XV | 22 | 17 | Northwich 3rd XV |