| Saturday, 6 September 2025 |
| Anselmians Mavericks (3rd XV) | v | Liverpool Collegiate 2nd XV |
| Ellesmere Port 2nd XV | v | Firwood Waterloo 3rd XV |
| Helsby | v | Liverpool St Helens FC 3rd XV Men |
| Mossley Hill | v | Southport 3rd XV |
| Oldershaw | v | Ormskirk 2nd XV |
| West Park (St Helens) 3rd XV | v | Wirral 3rd XV |
| Winnington Park 3rd XV | v | Prenton 2nd XV |
| Saturday, 13 September 2025 |
| Ellesmere Port 2nd XV | v | Oldershaw |
| Firwood Waterloo 3rd XV | v | West Park (St Helens) 3rd XV |
| Liverpool Collegiate 2nd XV | v | Helsby |
| Liverpool St Helens FC 3rd XV Men | v | Winnington Park 3rd XV |
| Mossley Hill | v | Prenton 2nd XV |
| Southport 3rd XV | v | Ormskirk 2nd XV |
| Wirral 3rd XV | v | Anselmians Mavericks (3rd XV) |
| Saturday, 20 September 2025 |
| Anselmians Mavericks (3rd XV) | v | Firwood Waterloo 3rd XV |
| Helsby | v | Wirral 3rd XV |
| Mossley Hill | v | Liverpool St Helens FC 3rd XV Men |
| Oldershaw | v | Southport 3rd XV |
| Ormskirk 2nd XV | v | Prenton 2nd XV |
| West Park (St Helens) 3rd XV | v | Ellesmere Port 2nd XV |
| Winnington Park 3rd XV | v | Liverpool Collegiate 2nd XV |
| Saturday, 27 September 2025 |
| Ellesmere Port 2nd XV | v | Anselmians Mavericks (3rd XV) |
| Firwood Waterloo 3rd XV | v | Helsby |
| Liverpool Collegiate 2nd XV | v | Mossley Hill |
| Liverpool St Helens FC 3rd XV Men | v | Ormskirk 2nd XV |
| West Park (St Helens) 3rd XV | v | Oldershaw |
| Wirral 3rd XV | v | Winnington Park 3rd XV |
| Saturday, 4 October 2025 |
| Anselmians Mavericks (3rd XV) | v | West Park (St Helens) 3rd XV |
| Helsby | v | Ellesmere Port 2nd XV |
| Mossley Hill | v | Wirral 3rd XV |
| Oldershaw | v | Prenton 2nd XV |
| Ormskirk 2nd XV | v | Liverpool Collegiate 2nd XV |
| Southport 3rd XV | v | Liverpool St Helens FC 3rd XV Men |
| Winnington Park 3rd XV | v | Firwood Waterloo 3rd XV |
| Saturday, 11 October 2025 |
| Anselmians Mavericks (3rd XV) | v | Oldershaw |
| Ellesmere Port 2nd XV | v | Winnington Park 3rd XV |
| Firwood Waterloo 3rd XV | v | Mossley Hill |
| Liverpool Collegiate 2nd XV | v | Southport 3rd XV |
| Liverpool St Helens FC 3rd XV Men | v | Prenton 2nd XV |
| West Park (St Helens) 3rd XV | v | Helsby |
| Wirral 3rd XV | v | Ormskirk 2nd XV |
| Saturday, 18 October 2025 |
| Helsby | v | Anselmians Mavericks (3rd XV) |
| Mossley Hill | v | Ellesmere Port 2nd XV |
| Oldershaw | v | Liverpool St Helens FC 3rd XV Men |
| Ormskirk 2nd XV | v | Firwood Waterloo 3rd XV |
| Prenton 2nd XV | v | Liverpool Collegiate 2nd XV |
| Southport 3rd XV | v | Wirral 3rd XV |
| Winnington Park 3rd XV | v | West Park (St Helens) 3rd XV |
| Saturday, 25 October 2025 |
| Anselmians Mavericks (3rd XV) | v | Winnington Park 3rd XV |
| Ellesmere Port 2nd XV | v | Ormskirk 2nd XV |
| Firwood Waterloo 3rd XV | v | Southport 3rd XV |
| Helsby | v | Oldershaw |
| Liverpool Collegiate 2nd XV | v | Liverpool St Helens FC 3rd XV Men |
| West Park (St Helens) 3rd XV | v | Mossley Hill |
| Wirral 3rd XV | v | Prenton 2nd XV |
| Saturday, 8 November 2025 |
| Liverpool St Helens FC 3rd XV Men | v | Wirral 3rd XV |
| Mossley Hill | v | Anselmians Mavericks (3rd XV) |
| Oldershaw | v | Liverpool Collegiate 2nd XV |
| Ormskirk 2nd XV | v | West Park (St Helens) 3rd XV |
| Prenton 2nd XV | v | Firwood Waterloo 3rd XV |
| Southport 3rd XV | v | Ellesmere Port 2nd XV |
| Winnington Park 3rd XV | v | Helsby |
| Saturday, 15 November 2025 |
| Anselmians Mavericks (3rd XV) | v | Ormskirk 2nd XV |
| Ellesmere Port 2nd XV | v | Prenton 2nd XV |
| Firwood Waterloo 3rd XV | v | Liverpool St Helens FC 3rd XV Men |
| Helsby | v | Mossley Hill |
| West Park (St Helens) 3rd XV | v | Southport 3rd XV |
| Winnington Park 3rd XV | v | Oldershaw |
| Wirral 3rd XV | v | Liverpool Collegiate 2nd XV |
| Saturday, 22 November 2025 |
| Liverpool Collegiate 2nd XV | v | Firwood Waterloo 3rd XV |
| Liverpool St Helens FC 3rd XV Men | v | Ellesmere Port 2nd XV |
| Mossley Hill | v | Winnington Park 3rd XV |
| Ormskirk 2nd XV | v | Helsby |
| Prenton 2nd XV | v | West Park (St Helens) 3rd XV |
| Southport 3rd XV | v | Anselmians Mavericks (3rd XV) |
| Wirral 3rd XV | v | Oldershaw |
| Saturday, 29 November 2025 |
| Prenton 2nd XV | v | Southport 3rd XV |
| Saturday, 6 December 2025 |
| Anselmians Mavericks (3rd XV) | v | Prenton 2nd XV |
| Ellesmere Port 2nd XV | v | Liverpool Collegiate 2nd XV |
| Firwood Waterloo 3rd XV | v | Wirral 3rd XV |
| Helsby | v | Southport 3rd XV |
| Mossley Hill | v | Oldershaw |
| West Park (St Helens) 3rd XV | v | Liverpool St Helens FC 3rd XV Men |
| Winnington Park 3rd XV | v | Ormskirk 2nd XV |
| Saturday, 13 December 2025 |
| Liverpool Collegiate 2nd XV | v | West Park (St Helens) 3rd XV |
| Liverpool St Helens FC 3rd XV Men | v | Anselmians Mavericks (3rd XV) |
| Oldershaw | v | Firwood Waterloo 3rd XV |
| Ormskirk 2nd XV | v | Mossley Hill |
| Prenton 2nd XV | v | Helsby |
| Southport 3rd XV | v | Winnington Park 3rd XV |
| Wirral 3rd XV | v | Ellesmere Port 2nd XV |
| Saturday, 20 December 2025 |
| Anselmians Mavericks (3rd XV) | v | Wirral 3rd XV |
| Helsby | v | Liverpool Collegiate 2nd XV |
| Oldershaw | v | Ellesmere Port 2nd XV |
| Ormskirk 2nd XV | v | Southport 3rd XV |
| Prenton 2nd XV | v | Mossley Hill |
| West Park (St Helens) 3rd XV | v | Firwood Waterloo 3rd XV |
| Winnington Park 3rd XV | v | Liverpool St Helens FC 3rd XV Men |
| Saturday, 10 January 2026 |
| Ellesmere Port 2nd XV | v | West Park (St Helens) 3rd XV |
| Firwood Waterloo 3rd XV | v | Anselmians Mavericks (3rd XV) |
| Liverpool Collegiate 2nd XV | v | Winnington Park 3rd XV |
| Liverpool St Helens FC 3rd XV Men | v | Mossley Hill |
| Prenton 2nd XV | v | Ormskirk 2nd XV |
| Southport 3rd XV | v | Oldershaw |
| Wirral 3rd XV | v | Helsby |
| Saturday, 17 January 2026 |
| Anselmians Mavericks (3rd XV) | v | Ellesmere Port 2nd XV |
| Helsby | v | Firwood Waterloo 3rd XV |
| Mossley Hill | v | Liverpool Collegiate 2nd XV |
| Oldershaw | v | West Park (St Helens) 3rd XV |
| Ormskirk 2nd XV | v | Liverpool St Helens FC 3rd XV Men |
| Southport 3rd XV | v | Prenton 2nd XV |
| Winnington Park 3rd XV | v | Wirral 3rd XV |
| Saturday, 24 January 2026 |
| Ellesmere Port 2nd XV | v | Helsby |
| Firwood Waterloo 3rd XV | v | Winnington Park 3rd XV |
| Liverpool Collegiate 2nd XV | v | Ormskirk 2nd XV |
| Liverpool St Helens FC 3rd XV Men | v | Southport 3rd XV |
| Prenton 2nd XV | v | Oldershaw |
| West Park (St Helens) 3rd XV | v | Anselmians Mavericks (3rd XV) |
| Wirral 3rd XV | v | Mossley Hill |
| Saturday, 31 January 2026 |
| Helsby | v | West Park (St Helens) 3rd XV |
| Mossley Hill | v | Firwood Waterloo 3rd XV |
| Oldershaw | v | Anselmians Mavericks (3rd XV) |
| Ormskirk 2nd XV | v | Wirral 3rd XV |
| Prenton 2nd XV | v | Liverpool St Helens FC 3rd XV Men |
| Southport 3rd XV | v | Liverpool Collegiate 2nd XV |
| Winnington Park 3rd XV | v | Ellesmere Port 2nd XV |
| Saturday, 14 February 2026 |
| Anselmians Mavericks (3rd XV) | v | Helsby |
| Ellesmere Port 2nd XV | v | Mossley Hill |
| Firwood Waterloo 3rd XV | v | Ormskirk 2nd XV |
| Liverpool Collegiate 2nd XV | v | Prenton 2nd XV |
| Liverpool St Helens FC 3rd XV Men | v | Oldershaw |
| West Park (St Helens) 3rd XV | v | Winnington Park 3rd XV |
| Wirral 3rd XV | v | Southport 3rd XV |
| Saturday, 21 February 2026 |
| Liverpool St Helens FC 3rd XV Men | v | Liverpool Collegiate 2nd XV |
| Mossley Hill | v | West Park (St Helens) 3rd XV |
| Oldershaw | v | Helsby |
| Ormskirk 2nd XV | v | Ellesmere Port 2nd XV |
| Prenton 2nd XV | v | Wirral 3rd XV |
| Southport 3rd XV | v | Firwood Waterloo 3rd XV |
| Winnington Park 3rd XV | v | Anselmians Mavericks (3rd XV) |
| Saturday, 28 February 2026 |
| Anselmians Mavericks (3rd XV) | v | Mossley Hill |
| Ellesmere Port 2nd XV | v | Southport 3rd XV |
| Firwood Waterloo 3rd XV | v | Prenton 2nd XV |
| Helsby | v | Winnington Park 3rd XV |
| Liverpool Collegiate 2nd XV | v | Oldershaw |
| West Park (St Helens) 3rd XV | v | Ormskirk 2nd XV |
| Wirral 3rd XV | v | Liverpool St Helens FC 3rd XV Men |
| Saturday, 7 March 2026 |
| Liverpool Collegiate 2nd XV | v | Wirral 3rd XV |
| Liverpool St Helens FC 3rd XV Men | v | Firwood Waterloo 3rd XV |
| Mossley Hill | v | Helsby |
| Oldershaw | v | Winnington Park 3rd XV |
| Ormskirk 2nd XV | v | Anselmians Mavericks (3rd XV) |
| Prenton 2nd XV | v | Ellesmere Port 2nd XV |
| Southport 3rd XV | v | West Park (St Helens) 3rd XV |
| Saturday, 21 March 2026 |
| Anselmians Mavericks (3rd XV) | v | Southport 3rd XV |
| Ellesmere Port 2nd XV | v | Liverpool St Helens FC 3rd XV Men |
| Firwood Waterloo 3rd XV | v | Liverpool Collegiate 2nd XV |
| Helsby | v | Ormskirk 2nd XV |
| Oldershaw | v | Wirral 3rd XV |
| West Park (St Helens) 3rd XV | v | Prenton 2nd XV |
| Winnington Park 3rd XV | v | Mossley Hill |
| Saturday, 11 April 2026 |
| Liverpool Collegiate 2nd XV | v | Ellesmere Port 2nd XV |
| Liverpool St Helens FC 3rd XV Men | v | West Park (St Helens) 3rd XV |
| Oldershaw | v | Mossley Hill |
| Ormskirk 2nd XV | v | Winnington Park 3rd XV |
| Prenton 2nd XV | v | Anselmians Mavericks (3rd XV) |
| Southport 3rd XV | v | Helsby |
| Wirral 3rd XV | v | Firwood Waterloo 3rd XV |
| Saturday, 18 April 2026 |
| Anselmians Mavericks (3rd XV) | v | Liverpool St Helens FC 3rd XV Men |
| Ellesmere Port 2nd XV | v | Wirral 3rd XV |
| Firwood Waterloo 3rd XV | v | Oldershaw |
| Helsby | v | Prenton 2nd XV |
| Mossley Hill | v | Ormskirk 2nd XV |
| West Park (St Helens) 3rd XV | v | Liverpool Collegiate 2nd XV |
| Winnington Park 3rd XV | v | Southport 3rd XV |
| Saturday, 25 April 2026 |
| Firwood Waterloo 3rd XV | v | Ellesmere Port 2nd XV |
| Liverpool Collegiate 2nd XV | v | Anselmians Mavericks (3rd XV) |
| Liverpool St Helens FC 3rd XV Men | v | Helsby |
| Ormskirk 2nd XV | v | Oldershaw |
| Prenton 2nd XV | v | Winnington Park 3rd XV |
| Southport 3rd XV | v | Mossley Hill |
| Wirral 3rd XV | v | West Park (St Helens) 3rd XV |