| Saturday, 6 September 2025 |
| Helsby | 39 | 7 | Liverpool St Helens FC 3rd XV Men |
| Mossley Hill | Home Walkover | Southport 3rd XV |
| Oldershaw | 103 | 12 | Ormskirk 2nd XV |
| West Park (St Helens) 3rd XV | 17 | 36 | Wirral 3rd XV |
| Winnington Park 3rd XV | 69 | 5 | Prenton 2nd XV |
| Saturday, 13 September 2025 |
| Ellesmere Port 2nd XV | 0 | 8 | Oldershaw |
| Firwood Waterloo 3rd XV | Away Walkover | West Park (St Helens) 3rd XV |
| Liverpool Collegiate 2nd XV | 15 | 33 | Helsby |
| Liverpool St Helens FC 3rd XV Men | 17 | 32 | Winnington Park 3rd XV |
| Mossley Hill | 10 | 64 | Prenton 2nd XV |
| Southport 3rd XV | 24 | 12 | Ormskirk 2nd XV |
| Saturday, 20 September 2025 |
| Helsby | 26 | 14 | Wirral 3rd XV |
| Mossley Hill | 0 | 48 | Liverpool St Helens FC 3rd XV Men |
| Oldershaw | 29 | 0 | Southport 3rd XV |
| Ormskirk 2nd XV | 0 | 39 | Prenton 2nd XV |
| West Park (St Helens) 3rd XV | 7 | 41 | Ellesmere Port 2nd XV |
| Winnington Park 3rd XV | Home Walkover | Liverpool Collegiate 2nd XV |
| Saturday, 27 September 2025 |
| Firwood Waterloo 3rd XV | 17 | 53 | Helsby |
| Liverpool Collegiate 2nd XV | 8 | 12 | Mossley Hill |
| Liverpool St Helens FC 3rd XV Men | 40 | 12 | Ormskirk 2nd XV |
| West Park (St Helens) 3rd XV | 31 | 14 | Oldershaw |
| Wirral 3rd XV | 21 | 5 | Winnington Park 3rd XV |
| Saturday, 4 October 2025 |
| Helsby | 24 | 20 | Ellesmere Port 2nd XV |
| Mossley Hill | 14 | 19 | Wirral 3rd XV |
| Ormskirk 2nd XV | 54 | 37 | Liverpool Collegiate 2nd XV |
| Southport 3rd XV | Home Walkover | Liverpool St Helens FC 3rd XV Men |
| Winnington Park 3rd XV | 34 | 24 | Firwood Waterloo 3rd XV |
| Saturday, 11 October 2025 |
| Ellesmere Port 2nd XV | 22 | 52 | Winnington Park 3rd XV |
| Firwood Waterloo 3rd XV | 17 | 73 | Mossley Hill |
| Liverpool Collegiate 2nd XV | 52 | 14 | Southport 3rd XV |
| West Park (St Helens) 3rd XV | 5 | 18 | Helsby |
| Wirral 3rd XV | 68 | 10 | Ormskirk 2nd XV |
| Saturday, 18 October 2025 |
| Oldershaw | 33 | 7 | Prenton 2nd XV |
| Ormskirk 2nd XV | 64 | 33 | Firwood Waterloo 3rd XV |
| Southport 3rd XV | 0 | 72 | Wirral 3rd XV |
| Winnington Park 3rd XV | 22 | 22 | West Park (St Helens) 3rd XV |
| Friday, 24 October 2025 |
| Firwood Waterloo 3rd XV | 45 | 31 | Southport 3rd XV |
| Saturday, 25 October 2025 |
| Helsby | 19 | 26 | Oldershaw |
| Liverpool Collegiate 2nd XV | 24 | 5 | Liverpool St Helens FC 3rd XV Men |
| West Park (St Helens) 3rd XV | 5 | 32 | Mossley Hill |
| Wirral 3rd XV | 55 | 7 | Prenton 2nd XV |
| Saturday, 8 November 2025 |
| Liverpool St Helens FC 3rd XV Men | 0 | 48 | Wirral 3rd XV |
| Ormskirk 2nd XV | 26 | 31 | West Park (St Helens) 3rd XV |
| Prenton 2nd XV | 36 | 19 | Firwood Waterloo 3rd XV |
| Winnington Park 3rd XV | 12 | 29 | Helsby |
| Friday, 14 November 2025 |
| Firwood Waterloo 3rd XV | 22 | 14 | Liverpool St Helens FC 3rd XV Men |
| Saturday, 15 November 2025 |
| Ellesmere Port 2nd XV | 56 | 17 | Prenton 2nd XV |
| Helsby | 34 | 10 | Mossley Hill |
| West Park (St Helens) 3rd XV | 48 | 10 | Southport 3rd XV |
| Winnington Park 3rd XV | 10 | 47 | Oldershaw |
| Wirral 3rd XV | 50 | 5 | Liverpool Collegiate 2nd XV |
| Saturday, 22 November 2025 |
| Liverpool Collegiate 2nd XV | 10 | 22 | Firwood Waterloo 3rd XV |
| Mossley Hill | Home Walkover | Winnington Park 3rd XV |
| Ormskirk 2nd XV | 5 | 35 | Helsby |
| Prenton 2nd XV | 36 | 14 | West Park (St Helens) 3rd XV |
| Wirral 3rd XV | Away Walkover | Oldershaw |
| Saturday, 29 November 2025 |
| Ellesmere Port 2nd XV | 50 | 5 | Firwood Waterloo 3rd XV |
| Oldershaw | Home Walkover | Liverpool St Helens FC 3rd XV Men |
| Saturday, 6 December 2025 |
| Mossley Hill | 10 | 12 | Oldershaw |
| West Park (St Helens) 3rd XV | 14 | 10 | Liverpool St Helens FC 3rd XV Men |
| Winnington Park 3rd XV | Home Walkover | Ormskirk 2nd XV |
| Saturday, 13 December 2025 |
| Liverpool Collegiate 2nd XV | 20 | 38 | West Park (St Helens) 3rd XV |
| Oldershaw | 35 | 0 | Firwood Waterloo 3rd XV |
| Ormskirk 2nd XV | 17 | 50 | Mossley Hill |
| Prenton 2nd XV | Home Walkover | Helsby |
| Southport 3rd XV | 10 | 31 | Winnington Park 3rd XV |
| Wirral 3rd XV | 49 | 31 | Ellesmere Port 2nd XV |
| Saturday, 20 December 2025 |
| Helsby | 41 | 12 | Liverpool Collegiate 2nd XV |
| Oldershaw | 5 | 5 | Ellesmere Port 2nd XV |
| West Park (St Helens) 3rd XV | 24 | 24 | Firwood Waterloo 3rd XV |
| Winnington Park 3rd XV | 19 | 31 | Liverpool St Helens FC 3rd XV Men |
| Saturday, 10 January 2026 |
| Ellesmere Port 2nd XV | 33 | 26 | West Park (St Helens) 3rd XV |
| Liverpool St Helens FC 3rd XV Men | 22 | 43 | Mossley Hill |
| Prenton 2nd XV | 29 | 29 | Ormskirk 2nd XV |
| Southport 3rd XV | 0 | 52 | Oldershaw |
| Winnington Park 3rd XV | Home Walkover | Liverpool Collegiate 2nd XV |
| Wirral 3rd XV | 12 | 19 | Helsby |
| Saturday, 17 January 2026 |
| Helsby | 26 | 26 | Firwood Waterloo 3rd XV |
| Mossley Hill | 31 | 22 | Liverpool Collegiate 2nd XV |
| Oldershaw | 41 | 0 | West Park (St Helens) 3rd XV |
| Ormskirk 2nd XV | 31 | 40 | Liverpool St Helens FC 3rd XV Men |
| Prenton 2nd XV | 43 | 10 | Southport 3rd XV |
| Prenton 2nd XV | 43 | 10 | Southport 3rd XV |
| Winnington Park 3rd XV | 10 | 39 | Wirral 3rd XV |
| Saturday, 24 January 2026 |
| Liverpool Collegiate 2nd XV | Home Walkover | Ormskirk 2nd XV |
| Prenton 2nd XV | 5 | 38 | Oldershaw |
| Southport 3rd XV | 12 | 40 | Liverpool St Helens FC 3rd XV Men |
| Wirral 3rd XV | 52 | 5 | Mossley Hill |
| Saturday, 31 January 2026 |
| Helsby | 61 | 5 | West Park (St Helens) 3rd XV |
| Mossley Hill | 31 | 5 | Firwood Waterloo 3rd XV |
| Ormskirk 2nd XV | 15 | 45 | Wirral 3rd XV |
| Prenton 2nd XV | 26 | 33 | Liverpool St Helens FC 3rd XV Men |
| Southport 3rd XV | 33 | 23 | Liverpool Collegiate 2nd XV |
| Winnington Park 3rd XV | 85 | 15 | Ellesmere Port 2nd XV |
| Saturday, 7 February 2026 |
| Ellesmere Port 2nd XV | 30 | 5 | Helsby |
| Liverpool St Helens FC 3rd XV Men | 22 | 25 | Prenton 2nd XV |
| Saturday, 14 February 2026 |
| Firwood Waterloo 3rd XV | 108 | 7 | Ormskirk 2nd XV |
| Liverpool Collegiate 2nd XV | 0 | 20 | Prenton 2nd XV |
| Liverpool Collegiate 2nd XV | Away Walkover | Prenton 2nd XV |
| Oldershaw | 62 | 0 | Liverpool St Helens FC 3rd XV Men |
| Wirral 3rd XV | Home Walkover | Southport 3rd XV |
| Friday, 20 February 2026 |
| Southport 3rd XV | 30 | 31 | Firwood Waterloo 3rd XV |
| Saturday, 21 February 2026 |
| Ellesmere Port 2nd XV | 29 | 41 | Ormskirk 2nd XV |
| Ellesmere Port 2nd XV | 29 | 41 | Ormskirk 2nd XV |
| Liverpool St Helens FC 3rd XV Men | 17 | 17 | Liverpool Collegiate 2nd XV |
| Mossley Hill | 36 | 12 | West Park (St Helens) 3rd XV |
| Oldershaw | 24 | 21 | Helsby |
| Prenton 2nd XV | 21 | 0 | Wirral 3rd XV |
| Saturday, 28 February 2026 |
| Firwood Waterloo 3rd XV | v | Prenton 2nd XV |
| Helsby | v | Winnington Park 3rd XV |
| Oldershaw | v | Liverpool Collegiate 2nd XV |
| Oldershaw | v | Liverpool Collegiate 2nd XV |
| Southport 3rd XV | v | Ellesmere Port 2nd XV |
| Southport 3rd XV | v | Ellesmere Port 2nd XV |
| West Park (St Helens) 3rd XV | v | Ormskirk 2nd XV |
| Wirral 3rd XV | v | Liverpool St Helens FC 3rd XV Men |
| Saturday, 7 March 2026 |
| Liverpool Collegiate 2nd XV | v | Wirral 3rd XV |
| Liverpool St Helens FC 3rd XV Men | v | Firwood Waterloo 3rd XV |
| Mossley Hill | v | Helsby |
| Oldershaw | v | Winnington Park 3rd XV |
| Prenton 2nd XV | v | Ellesmere Port 2nd XV |
| Southport 3rd XV | v | West Park (St Helens) 3rd XV |
| Saturday, 14 March 2026 |
| Firwood Waterloo 3rd XV | v | Winnington Park 3rd XV |
| Prenton 2nd XV | v | Mossley Hill |
| Saturday, 21 March 2026 |
| Ellesmere Port 2nd XV | v | Liverpool St Helens FC 3rd XV Men |
| Ellesmere Port 2nd XV | v | Liverpool St Helens FC 3rd XV Men |
| Firwood Waterloo 3rd XV | v | Liverpool Collegiate 2nd XV |
| Helsby | v | Ormskirk 2nd XV |
| Mossley Hill | v | Winnington Park 3rd XV |
| Oldershaw | v | Wirral 3rd XV |
| West Park (St Helens) 3rd XV | v | Prenton 2nd XV |
| Saturday, 28 March 2026 |
| Mossley Hill | v | Ellesmere Port 2nd XV |
| Mossley Hill | v | Ellesmere Port 2nd XV |
| Ormskirk 2nd XV | v | Southport 3rd XV |
| West Park (St Helens) 3rd XV | v | Winnington Park 3rd XV |
| Saturday, 11 April 2026 |
| Ellesmere Port 2nd XV | v | Liverpool Collegiate 2nd XV |
| Ellesmere Port 2nd XV | v | Liverpool Collegiate 2nd XV |
| Helsby | v | Southport 3rd XV |
| Helsby | v | Southport 3rd XV |
| Liverpool St Helens FC 3rd XV Men | v | West Park (St Helens) 3rd XV |
| Oldershaw | v | Mossley Hill |
| Ormskirk 2nd XV | v | Winnington Park 3rd XV |
| Wirral 3rd XV | v | Firwood Waterloo 3rd XV |
| Wirral 3rd XV | v | Firwood Waterloo 3rd XV |
| Saturday, 18 April 2026 |
| Ellesmere Port 2nd XV | v | Wirral 3rd XV |
| Firwood Waterloo 3rd XV | v | Oldershaw |
| Mossley Hill | v | Ormskirk 2nd XV |
| Prenton 2nd XV | v | Helsby |
| West Park (St Helens) 3rd XV | v | Liverpool Collegiate 2nd XV |
| Winnington Park 3rd XV | v | Southport 3rd XV |
| Saturday, 25 April 2026 |
| Firwood Waterloo 3rd XV | v | Ellesmere Port 2nd XV |
| Liverpool St Helens FC 3rd XV Men | v | Helsby |
| Mossley Hill | v | Southport 3rd XV |
| Ormskirk 2nd XV | v | Oldershaw |
| Prenton 2nd XV | v | Winnington Park 3rd XV |
| Wirral 3rd XV | v | West Park (St Helens) 3rd XV |